Law
Cram's Rule
Predicts the stereochemistry of nucleophilic attack on carbonyl groups adjacent to a chirality center.
Stereochemistry
Field: Stereochemistry
Sequence of Expressions
Determines the spatial configuration of products in the reaction of Grignard reagents with -keto esters.
Predicts the stereochemical outcome of nucleophilic addition to carbonyls with a chiral -carbon, considering steric and electronic effects.